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Michael Fenech Selected Research

4-nitrophenethyl bromide (NPB)

1/2017Infant birth outcomes are associated with DNA damage biomarkers as measured by the cytokinesis block micronucleus cytome assay: the DADHI study.
1/2014Extracellular amyloid beta 42 causes necrosis, inhibition of nuclear division, and mitotic disruption under both folate deficient and folate replete conditions as measured by the cytokinesis-block micronucleus cytome assay.
12/2007Cytokinesis-block micronucleus cytome assays for the determination of genotoxicity and cytotoxicity of cecal water in rats and fecal water in humans.
1/2006A comparison of folic acid deficiency-induced genomic instability in lymphocytes of breast cancer patients and normal non-cancer controls from a Chinese population in Yunnan.
1/2004Methylenetetrahydrofolate reductase C677T polymorphism, folic acid and riboflavin are important determinants of genome stability in cultured human lymphocytes.
3/2003Nucleoplasmic bridges are a sensitive measure of chromosome rearrangement in the cytokinesis-block micronucleus assay.

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Michael Fenech Research Topics

Disease

35Neoplasms (Cancer)
01/2022 - 11/2002
33Genomic Instability
09/2018 - 07/2002
17Chromosome Breakage
10/2016 - 03/2003
15Chromosomal Instability (Chromosome Stability)
10/2021 - 11/2002
10Alzheimer Disease (Alzheimer's Disease)
01/2020 - 11/2007
8Necrosis
11/2020 - 10/2003
7Breast Neoplasms (Breast Cancer)
09/2021 - 07/2004
7Chromosome Aberrations (Chromosome Abnormalities)
07/2021 - 12/2002
7Inflammation (Inflammations)
01/2021 - 01/2006
7Cognitive Dysfunction
01/2018 - 01/2012
6Folic Acid Deficiency (Folic Acid Deficiencies)
01/2022 - 01/2004
5Dementia (Dementias)
01/2020 - 08/2014
4Bites and Stings (Sting)
07/2021 - 10/2020
4Colorectal Neoplasms (Colorectal Cancer)
01/2021 - 12/2007
4Aneuploidy (Aneuploid)
10/2020 - 07/2004
4Malnutrition (Nutritional Deficiencies)
10/2016 - 06/2003
4Neurodegenerative Diseases (Neurodegenerative Disease)
06/2015 - 01/2009
4Carcinogenesis
07/2013 - 06/2009
3Chronic Disease (Chronic Diseases)
07/2021 - 09/2014
3Lung Neoplasms (Lung Cancer)
01/2011 - 05/2008
2Type 2 Diabetes Mellitus (MODY)
01/2022 - 10/2021
2Hematologic Neoplasms (Hematological Malignancy)
08/2021 - 02/2015
2Infections
07/2021 - 09/2014
2Prostatic Neoplasms (Prostate Cancer)
01/2021 - 12/2018
2Cardiovascular Diseases (Cardiovascular Disease)
03/2016 - 01/2011
2Pre-Eclampsia (Preeclampsia)
10/2015 - 04/2013
2Down Syndrome (Down's Syndrome)
07/2015 - 02/2008
2Iron Deficiencies
05/2012 - 01/2009
2Autistic Disorder (Autism)
04/2012 - 06/2010
2Infertility (Sterility)
01/2011 - 06/2003
2Weight Loss (Weight Reduction)
12/2010 - 06/2009
2Pain (Aches)
07/2010 - 01/2006
1Small Cell Lung Carcinoma (Small Cell Lung Cancer)
08/2021
1Myelodysplastic Syndromes (Myelodysplastic Syndrome)
08/2021
1Noncommunicable Diseases
07/2021
1RNA Virus Infections
07/2021
1Hyperglycemia
01/2021

Drug/Important Bio-Agent (IBA)

51Biomarkers (Surrogate Marker)IBA
01/2022 - 07/2002
26Folic Acid (Vitamin M)FDA LinkGeneric
03/2016 - 11/2002
22DNA (Deoxyribonucleic Acid)IBA
07/2021 - 12/2002
8MutagensIBA
10/2016 - 06/2003
7HomocysteineIBA
01/2018 - 01/2004
7MicronutrientsIBA
06/2015 - 11/2002
64-nitrophenethyl bromide (NPB)IBA
01/2017 - 03/2003
5Biological ProductsIBA
01/2021 - 05/2011
5Vitamin B 12 (Cyanocobalamin)FDA LinkGeneric
01/2017 - 07/2010
5Methionine (L-Methionine)FDA Link
10/2015 - 01/2003
5ZincIBA
06/2015 - 05/2005
5AntioxidantsIBA
06/2015 - 01/2006
5Proteins (Proteins, Gene)FDA Link
12/2010 - 12/2007
4Vitamin DFDA LinkGeneric
01/2021 - 05/2012
4ChromatinIBA
10/2020 - 02/2008
4CarcinogensIBA
10/2016 - 12/2002
4UracilIBA
05/2012 - 07/2004
3Apolipoproteins E (ApoE)IBA
01/2020 - 08/2014
3Vitamin B Complex (B Vitamins)IBA
01/2018 - 10/2015
3VitaminsIBA
11/2017 - 05/2005
3CarbonIBA
11/2017 - 10/2015
3CalciumIBA
10/2015 - 05/2005
3Amyloid beta-PeptidesIBA
01/2014 - 01/2007
3IronIBA
05/2012 - 01/2009
3Riboflavin (Vitamin B2)FDA LinkGeneric
01/2010 - 01/2004
2Glucose (Dextrose)FDA LinkGeneric
01/2022 - 11/2017
2Pyruvaldehyde (Methylglyoxal)IBA
01/2022 - 10/2021
2InterferonsIBA
07/2021 - 10/2020
2cyclic guanosine monophosphate-adenosine monophosphateIBA
07/2021 - 10/2020
2CytokinesIBA
07/2021 - 10/2015
2Reactive Oxygen Species (Oxygen Radicals)IBA
01/2021 - 04/2010
2XenobioticsIBA
09/2018 - 01/2018
2tau Proteins (tau Protein)IBA
11/2017 - 01/2007
2LipidsIBA
11/2017 - 08/2014
2EnzymesIBA
06/2016 - 10/2015
2Hormones (Hormone)IBA
06/2016 - 01/2015
2Vitamin B 6IBA
06/2016 - 04/2013
2polaprezinc (Z 103)IBA
06/2015 - 02/2011
2Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric
08/2014 - 01/2013
2Fatty Acids (Saturated Fatty Acids)IBA
08/2014 - 04/2014
2Cytostatic AgentsIBA
01/2014 - 04/2012
2Telomerase (Telomerase Reverse Transcriptase)IBA
06/2013 - 05/2012
2Choline (Choline Chloride)IBA
04/2012 - 01/2003
2CarbohydratesIBA
12/2010 - 05/2009
2PolyphenolsIBA
02/2009 - 01/2009
2Grape Seed ExtractIBA
02/2009 - 01/2009
2Molecular Probes (Molecular Probe)IBA
01/2008 - 01/2005
2Thymidine Monophosphate (TMP)IBA
01/2008 - 07/2004
2Biotin (Vitamin H)FDA Link
05/2005 - 07/2004
1LeptinIBA
09/2021
1Dietary FiberFDA Link
09/2021
1AdipokinesIBA
09/2021
1AdiponectinIBA
09/2021
1navitoclaxIBA
08/2021
1DecitabineFDA Link
08/2021
1A-Form DNA (A-DNA)IBA
08/2021
17,14-dihydroxypregn-4-ene-3,20-dioneIBA
07/2021
1RNA (Ribonucleic Acid)IBA
07/2021
1immune RNA (I-RNA)IBA
07/2021

Therapy/Procedure

5Therapeutics
01/2022 - 06/2015
4Radiotherapy
01/2017 - 06/2011
2Reducing Diet
12/2010 - 05/2009
1Precision Medicine
07/2021